Searchable abstracts of presentations at key conferences in endocrinology

ea0054oc5 | (1) | NuclearReceptors2018

The pathogenic role of estrogen receptor beta drives in endometriosis

Han Sang Jun , Jung Sung Yun , Wu San-Pin , Park Mi Jin , Qin Jun , Lydon John P , Tsai Sophia Y , Tsai Ming-Jer , DeMayo Francesco J , O'Malley Bert W

The defining feature of endometriosis is that endometrial tissues are deposited and grown onto sites outside of the uterine cavity. The pathogenesis of endometriosis, however, remains controversial despite extensive research. Since the endometriosis has been known as an estrogen-dependent inflammatory disease, the alterations in estrogen-mediated cellular signaling play an essential role in the pathogenesis of endometriosis. In addition to higher estrogen receptor (ER)β l...